Mesa (TRT) Testosterone Replacement Therapy

TRT with Enclomiphene: The Best TRT Protocol

MesaTRT uses enclomiphene with TRT for fertility protection, health benefits and avoiding testicular atrophy from low testosterone treatment.

Who Can Benefit from TRT with Enclomiphene?

TRT with enclomiphene is indicated for men experiencing symptoms of low testosterone who want to optimize their hormones while preserving future health and fertility.

Specific lab ranges that may warrant therapy include:

Total Testosterone

  • Under 300 ng/dL (nanograms per deciliter)

Free Testosterone

  • Under 50-90 pg/mL (picograms per milliliter)

Bioavailable Testosterone

  • Less than 110 ng/dL

Symptoms are key, but these testosterone thresholds give clinicians indication that a trial of enclomiphene and customized TRT may provide significant benefits for restoring strength, energy, endurance and vitality.

Protecting Testicular Function and Sperm Counts

By maintaining endogenous testosterone levels, enclomiphene prevents testicular shrinkage, atrophy and damage – a common side effect of testosterone-only replacement therapy.

One of the most important advantages of enclomiphene therapy is fertility protection for men wanting to conceive children in the future. Since enclomiphene maintains endogenous testosterone synthesis, the testes continue producing healthy sperm counts in most men. This allows patients who need testosterone replacement for symptom relief to also preserve their ability to biologically father children while undergoing treatment.

Enclomiphene stimulates the body’s production of luteinizing hormone (LH) and follicle stimulating hormone (FSH). This leads to increased natural testosterone synthesis while on TRT.

Comparing TRT with and without Enclomiphene

Traditional testosterone-only protocols come with considerable downsides that enclomiphene aims to mitigate.

TRT Without Enclomiphene

  • Suppresses natural testosterone
  • Higher cardiac risks
  • Accelerated hair loss for some
  • Potential mood instability
  • Complete loss of fertility
  • Testicular shrinkage

TRT With Enclomiphene

  • Preserves testosterone production
  • Lower risk profile
  • Maintains hair quality
  • Supports stable mood
  • Fertility protection
  • No testicular atrophy

Pros and Cons of Using Enclomiphene with TRT


  • Preserves fertility and spermatogenesis
  • Balances hormonal pathways
  • Lowers risk of heart problems
  • Stabilizes mood
  • No testicular shrinkage


  • Can elevate estrogen levels
  • Headaches in some users
  • Vision changes rarely

Let Us Help You Optimize Your Hormones

Dr. Scott Taylor incorporates enclomiphene into tailored testosterone replacement programs. Close patient monitoring and follow-up lab testing ensures treatment success.

For a free consultation contact Mesa TRT today and take a step toward your optimal health!

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